Noma Disease by
Eleto 2013/07/03 10:37
Noma Disease
Noma,also known as cancrum oris or gangrenous stomatitis, is a gangrenous disease leading to tissue destruction of the face, especially the mouth and cheek.
Causes
Noma is a rapidly progressive, polymicrobial, opportunistic infection that occurs during periods of compromised immune function. Fusobacterium necrophorum and Prevotella intermedia are thought to be key players in the process and interact with one or more other bacterial organisms (such as Borrelia vincentii, Porphyromonas gingivalis, Tannerella forsynthesis, Treponema denticola, Staphylococcus aureus, and nonhemolytic Streptococcus spp).
The reported predisposing factors include
*Malnutrition or dehydration
*Poor oral hygiene
*Poor sanitation
*Unsafe drinking water
*Proximity to unkempt livestock
*Recent illness
*Malignancy
*An immunodeficiency disorder, including AIDS
TreatMent
The progression of the disease can be halted with the use of antibiotics and improved nutrition; however, its physical effects are permanent and may require reconstructive plastic surgery to repair. Reconstruction is usually very challenging and should be delayed until full recovery (usually about one year following initial intervention).
This Sickness affects mostly children in Africa. To avoid Noma, Good nutrition must be provided and good sanitation.
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